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KMID : 1048120170060020094
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International Journal of Gastrointestinal Intervention
2017 Volume.6 No. 2 p.94 ~ p.101
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Comprehensive management of cholangiocarcinoma: Part II. Treatment
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Papafragkakis Charilaos
Lee Jeffrey H.
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Abstract
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Cholangioarcinoma is a rare but dreadful malignancy which poses much difficulties in the management. If detected early with only localized disease, curative resection is possible. However, most patients present in the late stages of the disease, which are managed with endoscopic biliary drainage and/or chemoradiation. Liver transplantation offers a possibility for cure in the distal and the perihilar tumors for selected candidates. Local treatments, such as hepatic artery-based therapies, brachytherapy, and photodynamic therapy, may offer some benefit in cases of the advanced disease. In this review, we will assess the role of preoperative biliary drainage, how best to drain biliary obstruction, and the intricate details of various treatments that are currently available.
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KEYWORD
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Cholangiocarcinoma, Cholestasis, Endoscopic ultrasonography, Liver transplantation, Self expandable metal stents
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